Lab-on-a-chip - 11/11/2020 Microfluidic platform for the best possible cancer therapy Every tumour and every patient is different, and there are individual reactions to drugs as well as the problem of resistance. Patient-specific cancer treatments require innovative and cost-effective approaches. The TheraMe! consortium has developed a novel instrument: a combination of microfluidic experiments and mathematical modelling for use in cancer precision medicine to prevent incorrect therapy options.https://biopro-v9-test-gi.xanium.io/en/article/news/microfluidic-platform-best-possible-cancer-therapy
Atriva Therapeutics - 21/10/2020 COVID-19 pioneer drug in Phase II clinical trial - with double the power The effective treatment of people with severe COVID-19 is a major goal during the corona pandemic. ATR-002, an oral small molecule that targets RNA viruses such as influenza virus and SARS-CoV-2, has a dual effect: it impairs viral propagation and also has an immunomodulatory effect. And what’s more, due to its unique cellular mechanism of action, the efficacy of Atrivia Therapeutics’ drug candidate is not reduced by virus mutations and…https://biopro-v9-test-gi.xanium.io/en/article/news/covid-19-pioneer-drug-phase-ii-clinical-trial-double-power
Article - 20/01/2020 Brain tumour patients could benefit from heavy ion therapy Glioblastoma is a malignant brain tumour. It does not respond anywhere near as well to conventional forms of therapy than other tumours because it contains particularly resistant cancer cells. Scientists at the Heidelberg Ion Beam Therapy Center (HIT) at Heidelberg University Hospital and the German Cancer Research Center have shown that heavy ion therapy is effective against these cells.https://biopro-v9-test-gi.xanium.io/en/article/news/Brain-tumour-patients-could-benefit-from-heavy-ion-therapy
Dossier - 06/12/2019 Microbiome: human health is closely connected with our microbial communities People have 1.3 times more microorganisms than body cells. This microbial community influences how we digest our food, how active our immune system is, as well as whether we tend to be more anxious or curious. A number of diseases have also been shown to be associated with a disturbed microbiome. Researchers still have a long way to go before the knowledge acquired can be used for developing therapies.https://biopro-v9-test-gi.xanium.io/en/article/dossier/microbiome-human-health-closely-connected-with-microbial-communities
Article - 05/08/2019 The answer to antibiotic resistance may lie in the microbiome Globally, increasing numbers of bacteria are becoming resistant to common antibiotics. Moreover, many reserve group antibiotics are no longer effective for infections caused by multidrug-resistant pathogens. Researchers in an excellence cluster at the University of Tübingen are investigating an alternative approach to combating bacterial infections. Their goal is to specifically influence the microbiome, the human microbial community.https://biopro-v9-test-gi.xanium.io/en/article/news/answer-to-antibiotic-resistance-may-lie-in-the-microbiome
New edition - 24/05/2019 Tumour metastasis Cancer is usually not curable when metastases have formed in the body. Metastases are often resistant to drugs that have successfully eliminated the primary tumour. The basic features of the complex process of metastasis are now known, but many details still remain elusive. Intensive research activities are focusing on new therapeutic concepts aimed at developing effective anti-metastatic therapies.https://biopro-v9-test-gi.xanium.io/en/article/dossier/tumour-metastasis
Article - 16/04/2019 Tumour monitoring using liquid biopsy Liquid biopsy, the analysis of cancer biomarkers and circulating tumour cells in body fluids such as blood, is revolutionising the diagnosis and monitoring of cancer. It has also been possible to expand circulating tumour cells from the blood under laboratory conditions. It is expected that in the future, liquid biopsy will be able to precisely characterise tumour cells at every stage of a cancer.https://biopro-v9-test-gi.xanium.io/en/article/news/tumour-monitoring-using-liquid-biopsy
Article - 24/01/2019 Scientists to combat antibiotic-resistant bacteria in wastewater In Germany, around 1,500 tonnes of antibiotics per year are administered to humans and animals. As a result, more and more bacteria are developing resistance to common antibiotics. As part of HyReKA, a cooperative project funded by the BMBF, scientists led by Professor Thomas Schwartz from the KIT are investigating how antibiotic-resistant pathogens spread and how they can be prevented from doing so.https://biopro-v9-test-gi.xanium.io/en/article/news/scientists-to-combat-antibiotic-resistant-bacteria-in-wastewater
Dossier - 28/08/2018 With molecular diagnostics to biomarker-based personalised therapy Diagnosing suitable biomarkers is a prerequisite for tailoring personalised therapies to patient heterogeneity. Genetic tests and genome sequencing play a key role in these diagnoses. Up until now, personalised therapy has achieved the greatest success in the field of oncology. However, personalised treatments are also gaining in importance for treating other diseases.https://biopro-v9-test-gi.xanium.io/en/article/dossier/with-molecular-diagnostics-to-biomarker-based-personalised-therapy
Funding Future Insight Prize Funding programme, Funded by: Merck KGaA, sb_search.searchresult.label.programSubmissionDate: 31/12/2022 https://biopro-v9-test-gi.xanium.io/en/database/funding/future-insight-prize
Dossier - 16/06/2014 Biotechnology as a tool for the production of food Biotechnology opens up numerous opportunities for the food industry. The targeted use of biotechnological methods can help reduce the quantity and number of unhealthy ingredients in foods as well as degrade allergenic substances. Genomic research and targeted breeding also greatly facilitate progress in agriculture. Food biotechnology therefore contributes significantly to saving resources, optimising harvest yields and producing better foods.https://biopro-v9-test-gi.xanium.io/en/article/dossier/biotechnology-as-a-tool-for-the-production-of-food
Dossier - 02/06/2014 Bioanalysis techniques for the characterization of biological material Science constantly provides researchers with new challenges biologists and bioanalysts have to deal with and which come from sources as varied as the ever increasing number of resistant pathogenic bacterial strains or the famine conditions in Third-World countries. In the search for scientific truths bioanalysis is the development optimization and application of the entire range of analytical methods available. However we need to keep in mind…https://biopro-v9-test-gi.xanium.io/en/article/dossier/bioanalysis-techniques-for-the-characterization-of-biological-material
Dossier - 10/02/2014 Multiresistant pathogens a self-inflicted threat? Most bacterial infections have lost their capacity to cause terror thanks to antibiotics. However, the increase in antibiotic resistances is making the fight against bacterial pathogens rather difficult, and the widespread overuse and inappropriate use of antibiotics continues to fuel the increase in antibiotic-resistant bacteria. https://biopro-v9-test-gi.xanium.io/en/article/dossier/multiresistant-pathogens-a-self-inflicted-threat
Dossier - 15/10/2013 Adult stem cells hope for regenerative therapies Adult stem cells have the lifelong ability to generate new specialised cells. They secure the continuous replenishment of cells therefore enabling the constant replacement of dying cells with new ones. Progress in the characterisation isolation and specific differentiation of adult stem cells over recent years raises hopes for the future use of the cells in the therapy of degenerative diseases. Knowledge about adult stem cells also has the…https://biopro-v9-test-gi.xanium.io/en/article/dossier/adult-stem-cells-hope-for-regenerative-therapies
Dossier - 23/07/2012 Extremophilic bacteria Extremophilic bacteria love it hot, sour or salty, toxic substances like heavy metals also do them good and even give them energy. As molecular and systems biology techniques get better and better, industry is also becoming increasingly interested in these exotic organisms. What potential does knowing the biochemistry of extremophilic bacteria have for the pharmaceutical, cosmetics and sanitary articles industries? https://biopro-v9-test-gi.xanium.io/en/article/dossier/extremophilic-bacteria
Dossier - 30/04/2012 Human infectious diseases new threats The serious EHEC outbreak in Germany in 2011, the 2009 swine flu pandemic, the bird flu pandemic in 2005 and 2006 and the SARS outbreak in China in 2003, all of which have fuelled the fear of devastating epidemics for many people in Germany, have fortunately all been contained – at least up until now. However, experts warn of new dangerous pathogens that are spreading as a result of globalization and global climate warming. https://biopro-v9-test-gi.xanium.io/en/article/dossier/human-infectious-diseases-new-threats
