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  • Article - 22/03/2019 Prof. Lichter (left) and Prof. Schneeweiss, who run the Translational Breast Cancer Programme in Heidelberg, in the laboratory

    Personalised therapies for treating metastasing breast cancer

    Breast cancer is characterised by broad genetic diversity. Successful treatment is made even more difficult by the fact that, in advanced breast cancer, the properties of metastases often differ significantly from the primary tumour. The Heidelberg CATCH study is now collecting genetic profiles from patients' metastasis tissue samples, which can be used to tailor therapy to individual requirements.

    https://biopro-v9-test-gi.xanium.io/en/article/news/personalisierte-therapieansaetze-bei-metastasiertem-brustkrebs
  • Article - 18/03/2019 European Union flag in the wind.

    EHR and PHR: digital records in the German healthcare system

    EHRs, i.e. electronic health records (German: Patientenakte, ePA), are hailed as the key to increasing the quality of care. The Appointment Service and Supply Act (TSVG), adopted on 14th March 2019, requires the German statutory health insurance funds to provide policyholders with electronic health records from 1st January 2021 onwards.

    https://biopro-v9-test-gi.xanium.io/en/article/news/ehr-and-phr-digital-records-in-the-german-healthcare-system
  • Dossier - 28/08/2018 Woman wearing a white lab coat in a laboratory looking at a tube she is holding in her hand.

    With molecular diagnostics to biomarker-based personalised therapy

    Diagnosing suitable biomarkers is a prerequisite for tailoring personalised therapies to patient heterogeneity. Genetic tests and genome sequencing play a key role in these diagnoses. Up until now, personalised therapy has achieved the greatest success in the field of oncology. However, personalised treatments are also gaining in importance for treating other diseases.

    https://biopro-v9-test-gi.xanium.io/en/article/dossier/with-molecular-diagnostics-to-biomarker-based-personalised-therapy
  • Dossier - 17/01/2017 Photo of the extraction procedure used to produce medicinal extracts. Two tube-shaped containers that are connected with each other by other tubes contain a brown liquid. Dr. Willmar Schwabe GmbH & Co. KG uses state-of-the-art methods to produce extracts for herbal medicines.

    Phytopharmaceuticals – fighting disease with natural substances

    Phytopharmaceuticals are herbal medicines whose efficacy is down to one or several plant substances or active ingredients. They have been used for treating diseases since time immemorial. This traditional knowledge is still the basis for many medicinal products made from plants or parts thereof. Herbal medicines have been produced in Baden-Württemberg for many generations.

    https://biopro-v9-test-gi.xanium.io/en/article/dossier/phytopharmaceuticals-fighting-disease-with-natural-substances
  • Dossier - 14/06/2016 Schematic showing the defence chain of a prokaryote with CRISPR/Cas - integration of a phage genome into the CRISPR array and an infection of another phage whose genome is already "known" in the array. The new piece of DNA is immediately destroyed by the CRISPR/Cas complex.

    CRISPR/Cas – genome editing is becoming increasingly popular

    The number of publications and patents that involve the CRISPR/Cas system has been increasing exponentially since the technique was first described a few years ago. The increase in funding for projects involving CRISPR/Cas also demonstrates how powerful this new method is. The targeted modification of genomes (also called gene or genome editing) using CRISPR/Cas is extraordinarily accurate and also has the potential to cure hereditary diseases.

    https://biopro-v9-test-gi.xanium.io/en/article/dossier/crisprcas-genome-editing-is-becoming-increasingly-popular
  • Overview

    Pharmaceutics

    https://biopro-v9-test-gi.xanium.io/en/article/pharma
  • The Baden-Württemberg healthcare industry

    The pharmaceutical industry

    https://biopro-v9-test-gi.xanium.io/en/location/pharma
  • Dossier - 13/04/2015 In Germany, young girls can now protect themselves from cervical cancer. (Photo: NCI)

    Boosting the immune system can improve cancer prevention and treatment

    The activation of the body’s immune system to fight cancer is not only a promising therapeutic concept, but is already used in medical practice. The first immunotherapies have been approved and many more are either in the experimental stages or already undergoing clinical testing. Vaccines to prevent certain types of cancer are already being used successfully around the world.

    https://biopro-v9-test-gi.xanium.io/en/article/dossier/boosting-the-immune-system-can-improve-cancer-prevention-and-treatment
  • Dossier - 10/11/2014 22065_de.jpg

    Cell and gene therapies from bench to bedside

    https://biopro-v9-test-gi.xanium.io/en/article/dossier/cell-and-gene-therapies-from-bench-to-bedside
  • Dossier - 04/11/2013 Glass bioreactor filled with a red liquid.

    Biotechnology driver of innovation in the pharmaceutical industry

    The biotech industry is the innovative driver for a pharmaceutical industry that, due to the shift from blockbluster products to personalised medicine, now depends on new concepts. The production of new drugs using genetic engineering relies on knowledge gained from genomics, proteomics and systems biology and creates new treatment strategies that combine therapy and diagnostics (i.e. companion diagnostics) to provide a specific individualised…

    https://biopro-v9-test-gi.xanium.io/en/article/dossier/biotechnology-driver-of-innovation-in-the-pharmaceutical-industry
  • Dossier - 15/10/2013 The photo shows a piece of cartilage in a test tube.

    Adult stem cells hope for regenerative therapies

    Adult stem cells have the lifelong ability to generate new specialised cells. They secure the continuous replenishment of cells therefore enabling the constant replacement of dying cells with new ones. Progress in the characterisation isolation and specific differentiation of adult stem cells over recent years raises hopes for the future use of the cells in the therapy of degenerative diseases. Knowledge about adult stem cells also has the…

    https://biopro-v9-test-gi.xanium.io/en/article/dossier/adult-stem-cells-hope-for-regenerative-therapies
  • Dossier - 21/05/2013 A pile of tablets

    No new drugs to be placed on the market without clinical trials

    New pharmaceuticals are subject to approval by drug authorities. Here clinical trials are performed to ensure the quality efficacy and safety of a medicinal product. Clinical development is a time-consuming and costly process and takes on average ten to fifteen years before a pharmaceutical company can apply for the approval of the drug. The costs including failures can amount to approximately one billion US dollars per drug.

    https://biopro-v9-test-gi.xanium.io/en/article/dossier/no-new-drugs-to-be-placed-on-the-market-without-clinical-trials
  • Dossier - 01/04/2013 19423_de.jpg

    Retroviruses from infectious agent to therapeutic assistant

    Viruses are infectious particles that use the machinery and metabolism of a host cell to replicate. The family of retroviruses is particularly known for its most notorious representative i. e. the human immunodeficiency virus HIV. However retroviruses are not only of interest for researchers looking for effective cures for viral infections their characteristic properties also make them promising laboratory and gene therapy tools.

    https://biopro-v9-test-gi.xanium.io/en/article/dossier/retroviruses-from-infectious-agent-to-therapeutic-assistant
  • Dossier - 26/11/2012 Electron micrograph of fluorescence-stained chromosomes

    Genetic diagnostics technology reaches the limits of what is medically reasonable

    Rapid progress in sequencing technologies is poised to set the imagination of biomedical researchers on fire. Experts now believe that progress is about to make possible what seemed to be utopian a few years ago – it seems likely that it will soon be possible to sequence the human genome in only a few minutes and store and automatically analyse it using tiny automates. However, is everything that is technically feasible also reasonable?

    https://biopro-v9-test-gi.xanium.io/en/article/dossier/genetic-diagnostics-technology-reaches-the-limits-of-what-is-medically-reasonable

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